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Congenital disease SNPs target lineage specific structural elements in protein kinases
The catalytic domain of protein kinases harbors a large number of disease-causing single nucleotide polymorphisms (SNPs) and common or neutral SNPs that are not known or hypothesized to be associated with any disease. Distinguishing these two types of polymorphisms is critical in accurately predicti...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2449356/ https://ncbi.nlm.nih.gov/pubmed/18579784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802403105 |
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