Effects of ciprofloxacin on plasmid DNA supercoiling of Escherichia coli topoisomerase I and gyrase mutants.

Changes in plasmid DNA supercoiling were measured following treatment of Escherichia coli cells, carrying topoisomerase mutations, with the quinolone ciprofloxacin. In quinolone-susceptible cells (top+ gyr+) as well as in topA mutants and in gyrB mutants, plasmid DNA was relaxed after the addition o...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Aleixandre, V, Herrera, G, Urios, A, Blanco, M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC244935/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1849710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.35.1.20
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