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Remodeling the exocrine pancreas at metamorphosis in Xenopus laevis

At metamorphosis the Xenopus laevis tadpole exocrine pancreas remodels in two stages. At the climax of metamorphosis thyroid hormone (TH) induces dedifferentiation of the entire exocrine pancreas to a progenitor state. The organ shrinks to 20% of its size, and ≈40% of its cells die. The acinar cells...

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Detalles Bibliográficos
Main Authors: Mukhi, Sandeep, Mao, Jinzhe, Brown, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2449347/
https://ncbi.nlm.nih.gov/pubmed/18574144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803569105
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