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X-ray absorption spectroscopic characterization of a cytochrome P450 compound II derivative

The cytochrome P450 enzyme CYP119, its compound II derivative, and its nitrosyl complex were studied by iron K-edge x-ray absorption spectroscopy. The compound II derivative was prepared by reaction of the resting enzyme with peroxynitrite and had a lifetime of ≈10 s at 23°C. The CYP119 nitrosyl com...

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Autors principals: Newcomb, Martin, Halgrimson, James A., Horner, John H., Wasinger, Erik C., Chen, Lin X., Sligar, Stephen G.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2448811/
https://ncbi.nlm.nih.gov/pubmed/18174331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708299105
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