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APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa

The bone marrow constitutes a favorable environment for long-lived antibody-secreting plasma cells, providing blood-circulating antibody. Plasma cells are also present in mucosa-associated lymphoid tissue (MALT) to mediate local frontline immunity, but how plasma cell survival there is regulated is...

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Hlavní autoři: Huard, Bertrand, McKee, Thomas, Bosshard, Carine, Durual, Stéphane, Matthes, Thomas, Myit, Samir, Donze, Olivier, Frossard, Christophe, Chizzolini, Carlo, Favre, Christiane, Zubler, Rudolf, Guyot, Jean Philippe, Schneider, Pascal, Roosnek, Eddy
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447926/
https://ncbi.nlm.nih.gov/pubmed/18618015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33760
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