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Thymidylate Synthase, Thymidine Phosphorylase and Orotate Phosphoribosyl Transferase Levels as Predictive Factors of Chemotherapy in Oral Squamous Cell Carcinoma

We conducted a clinicopathologic study on protein and mRNA levels of thymidylate synthase (TS), thymidine phosphorylase (TP) and orotate phosphoribosyl transferase (OPRT) using biopsy tissue specimens before treatment. The mRNA levels have been measured in tumor cells microdissected from paraffin-em...

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Autori principali: Ogiuchi, Yosuke, Maruoka, Yasubumi, Ando, Tomohiro, Kobayashi, Makio, Ogiuchi, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japan Society of Histochemistry and Cytochemistry 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447914/
https://ncbi.nlm.nih.gov/pubmed/18636111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/ahc.08002
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