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Playing both sides: nucleophosmin between tumor suppression and oncogenesis
Nucleophosmin (NPM) is frequently mutated in acute myeloid leukemias and is thought to act as both a proto-oncogene and a tumor suppressor. Although genetic and molecular evidence has shed light on the mechanisms of NPM-mediated tumor suppression, the potential role of NPM mutants as oncogenes remai...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2008
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447893/ https://ncbi.nlm.nih.gov/pubmed/18625839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200806069 |
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