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Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation

Atherosclerotic plaques develop in regions of the vasculature associated with chronic inflammation due to disturbed flow patterns. Endothelial phenotype modulation by flow requires the integration of numerous mechanotransduction pathways, but how this is achieved is not well understood. We show here...

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Detalhes bibliográficos
Main Authors: Liu, Yunhao, Sweet, Daniel Timothy, Irani-Tehrani, Mohamad, Maeda, Nobuyo, Tzima, Ellie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447891/
https://ncbi.nlm.nih.gov/pubmed/18606845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200709176
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