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Isolation of a Drosophila amplification origin developmentally activated by transcription

We exploited the Drosophila Amplicon in Follicle Cells, DAFC-62D, to identify a new metazoan amplification origin, ori62. In addition to the origin, DAFC-62D contains two other developmental stage-specific binding regions for the Origin Recognition Complex (ORC) and the replicative helicase MCM2–7....

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Bibliographic Details
Main Authors: Xie, Fang, Orr-Weaver, Terry L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447865/
https://ncbi.nlm.nih.gov/pubmed/18621687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804146105
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