Toll-like Receptor 4 Mediates Induction of the Bcl10-NFκB-Interleukin-8 Inflammatory Pathway by Carrageenan in Human Intestinal Epithelial Cells

The sulfated polysaccharide carrageenan (CGN) induces activation of NFκB and interleukin 8 (IL-8) in human colonic epithelial cells through a pathway of innate immunity mediated by Bcl10 (B-cell CLL/lymphoma 10). In this report, we identify Toll-like receptor 4 (TLR4), a member of the family of inna...

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Autores principales: Bhattacharyya, Sumit, Gill, Ravinder, Chen, Mei Ling, Zhang, Fuming, Linhardt, Robert J., Dudeja, Pradeep K., Tobacman, Joanne K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
Materias:
Mechanisms of Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447641/
https://ncbi.nlm.nih.gov/pubmed/18252714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708833200
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