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Protein C as a surrogate end-point for clinical trials of sepsis

Identification of good surrogate end-points can greatly facilitate the design of clinical trials. Using data from PROWESS and ENHANCE, Shorr and colleagues explore the potential value of several plasma biomarkers for treatment trials of activated protein C for severe sepsis. Based on the framework p...

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Detalhes bibliográficos
Main Authors: Liu, Kathleen D, Matthay, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447596/
https://ncbi.nlm.nih.gov/pubmed/18492215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6859
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