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Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)

INTRODUCTION: Drotrecogin alfa (activated; DrotAA) treatment, a 96-hour infusion, reduces 28-day mortality in severe sepsis to approximately 25%. The question remains whether a longer infusion or higher dose could increase rate of survival. The goal of this study was to identify a dependable, sensit...

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Autors principals: Shorr, Andrew F, Nelson, David R, Wyncoll, Duncan LA, Reinhart, Konrad, Brunkhorst, Frank, Vail, George Matthew, Janes, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447591/
https://ncbi.nlm.nih.gov/pubmed/18394162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc6854
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