ProbSeq—A Fragmentation Model for Interpretation of Electrospray Tandem Mass Spectrometry Data

We describe a probabilistic peptide fragmentation model for use in protein databank searching and de novo sequencing of electrospray tandem mass spectrometry data. A probabilistic framework for tuning of the model using a range of well-characterized samples are introduced. We present preliminary res...

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Main Authors: Skilling, John, Denny, Richard, Richardson, Keith, Young, Phillip, McKenna, Thérèse, Campuzano, Iain, Ritchie, Mark
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2004
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447321/
https://ncbi.nlm.nih.gov/pubmed/18629038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cfg.370
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