Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers

The genus Alphavirus contains members that threaten human health, both as natural pathogens and as potential biological weapons. Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) enter cells readily and can inhibit viral replication through sequence-specific steric blockade of viral...

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Autores principales: Paessler, Slobodan, Rijnbrand, Rene, Stein, David A., Ni, Haolin, Yun, Nadezhda E., Dziuba, Natallia, Borisevich, Viktoriya, Seregin, Alexey, Ma, Yinghong, Blouch, Robert, Iversen, Patrick L., Zacks, Michele A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Inc. 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447162/
https://ncbi.nlm.nih.gov/pubmed/18468653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.03.032
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