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Extracellular Signals Regulate Rapid Coactivator Recruitment at AP-1 Sites by Altered Phosphorylation of both CREB Binding Protein and c-jun

Retinoic acid (RA) inhibits matrix metalloproteinase 9 (MMP-9) expression due to AP-1 inhibition resulting from retinoic acid receptors (RARs) competing for limiting amounts of coactivator proteins. However, given the rapid kinetics of MMP-9 transcription, it seems unlikely that these interactions c...

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Autors principals: Tsai, Linh N., Ku, Tony K. S., Salib, Nader K., Crowe, David L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447142/
https://ncbi.nlm.nih.gov/pubmed/18443043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01489-07
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