Identification of a Physiological Phosphorylation Site of the Herpes Simplex Virus 1-Encoded Protein Kinase Us3 Which Regulates Its Optimal Catalytic Activity In Vitro and Influences Its Function in Infected Cells

Us3 is a serine/threonine protein kinase encoded by herpes simplex virus 1 (HSV-1). Here, we report the identification of a physiological Us3 phosphorylation site on serine at position 147 (Ser-147) which regulates its protein kinase activity in vitro. Moreover, mutation of this site influences Us3...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Kato, Akihisa, Tanaka, Michiko, Yamamoto, Mayuko, Asai, Risa, Sata, Tetsutaro, Nishiyama, Yukihiro, Kawaguchi, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447112/
https://ncbi.nlm.nih.gov/pubmed/18417577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00044-08
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares