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Molecular Basis of Cytotoxicity of Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) in EBV Latency III B Cells: LMP1 Induces Type II Ligand-Independent Autoactivation of CD95/Fas with Caspase 8-Mediated Apoptosis
The Epstein-Barr virus (EBV) oncoprotein latent membrane protein 1 (LMP1) is thought to act as the major transforming protein in various cell types, by rerouting the tumor necrosis factor receptor family signaling pathway. Despite this implication in EBV-associated transformation of cells, LMP1 toxi...
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Autors principals: | , , , , , , , , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
American Society for Microbiology (ASM)
2008
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447067/ https://ncbi.nlm.nih.gov/pubmed/18448526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02250-07 |
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