The Evolution of Class 1 Integrons and the Rise of Antibiotic Resistance

Class 1 integrons are central players in the worldwide problem of antibiotic resistance, because they can capture and express diverse resistance genes. In addition, they are often embedded in promiscuous plasmids and transposons, facilitating their lateral transfer into a wide range of pathogens. Un...

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Bibliographic Details
Main Authors: Gillings, Michael, Boucher, Yan, Labbate, Maurizio, Holmes, Andrew, Krishnan, Samyuktha, Holley, Marita, Stokes, H. W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447024/
https://ncbi.nlm.nih.gov/pubmed/18487337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00152-08
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