Differential Antigen Requirements for Protection against Systemic and Intranasal Vaccinia Virus Challenges in Mice

The development of a subunit vaccine for smallpox represents a potential strategy to avoid the safety concerns associated with replication-competent vaccinia virus. Preclinical studies to date with subunit smallpox vaccine candidates, however, have been limited by incomplete information regarding pr...

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Main Authors: Kaufman, David R., Goudsmit, Jaap, Holterman, Lennart, Ewald, Bonnie A., Denholtz, Matthew, Devoy, Colleen, Giri, Ayush, Grandpre, Lauren E., Heraud, Jean-Michel, Franchini, Genoveffa, Seaman, Michael S., Havenga, Menzo J. E., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2008
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446990/
https://ncbi.nlm.nih.gov/pubmed/18448519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00353-08
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