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Aberrant Lymphocyte Activation Precedes Delayed Virus-Specific T-Cell Response after both Primary Infection and Secondary Exposure to Hepadnavirus in the Woodchuck Model of Hepatitis B Virus Infection

The contribution of virus-specific T lymphocytes to the outcome of acute hepadnaviral hepatitis is well recognized, but a reason behind the consistent postponement of this response remains unknown. Also, the characteristics of T-cell reactivity following reexposure to hepadnavirus are not thoroughly...

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Detalhes bibliográficos
Main Authors: Gujar, Shashi A., Jenkins, Adam K., Guy, Clifford S., Wang, Jinguo, Michalak, Tomasz I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446969/
https://ncbi.nlm.nih.gov/pubmed/18480439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00661-08
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