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Infection with Vpr-Positive Human Immunodeficiency Virus Type 1 Impairs NK Cell Function Indirectly through Cytokine Dysregulation of Infected Target Cells

Human immunodeficiency virus type 1 (HIV-1) infection has been implicated in impairing various aspects of NK cell function in viremic condition, and several viral factors contribute to these defects. Here, we evaluated the effect of HIV-1 Vpr on NK cell cytolytic function and cytokine (gamma interfe...

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Detalhes bibliográficos
Main Authors: Majumder, Biswanath, Venkatachari, Narasimhan J., O'Leary, Shaylee, Ayyavoo, Velpandi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446960/
https://ncbi.nlm.nih.gov/pubmed/18417583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01979-07
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