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Direct Interactions between the Paf1 Complex and a Cleavage and Polyadenylation Factor Are Revealed by Dissociation of Paf1 from RNA Polymerase II

The Paf1 complex (Paf1, Ctr9, Cdc73, Rtf1, and Leo1) is normally associated with RNA polymerase II (Pol II) throughout the transcription cycle. However, the loss of either Rtf1 or Cdc73 results in the detachment of the Paf1 complex from Pol II and the chromatin form of actively transcribed genes. Us...

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Detalhes bibliográficos
Main Authors: Nordick, Kristen, Hoffman, Matthew G., Betz, Joan L., Jaehning, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446681/
https://ncbi.nlm.nih.gov/pubmed/18469135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00434-07
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