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Protein-protein docking with reduced potentials by exploiting multi-dimensional energy funnels

We propose a new computational approach for protein docking exploiting energy funnels in the 6-dimensional space of translations and rotations of the ligand with respect to the receptor. Our approach consists of a series of translational and orientational moves of the ligand towards the receptor. Ea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Paschalidis, Ioannis Ch., Shen, Yang, Vakili, Pirooz, Vajda, Sandor
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446401/
https://ncbi.nlm.nih.gov/pubmed/17946298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/IEMBS.2006.260790
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