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Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrow
We have identified a rare (≈0.05–0.1%) population of cells (Thy-1(hi)CD16(+)CD44(hi)CD2(−)TCRαβ(−)B220(−)Mac-1(−)NK1.1(−)) in the adult mouse bone marrow that generates CD4(+) and CD8(+) TCRαβ(+) T cells after tissue culture for 48 hr in the presence of Ly5 congenic marrow cells. The essential stage...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24464/ https://ncbi.nlm.nih.gov/pubmed/10588733 |
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