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The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue

BACKGROUND: Sulphur mustard gas, 2, 2'-dichlorodiethyl sulphide (HD), is a chemical warfare agent. Both mustard gas and its monofunctional analogue, 2-chloroethyl ethyl sulphide (CEES), are alkylating agents that react with and diminish cellular thiols and are highly toxic. Previously, we repor...

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Autori principali: Paromov, Victor, Qui, Min, Yang, Hongsong, Smith, Milton, Stone, William L
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2446388/
https://ncbi.nlm.nih.gov/pubmed/18570648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-33
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