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Crystallization and preliminary crystallographic analysis of merohedrally twinned crystals of MJ0729, a CBS-domain protein from Methanococcus jannaschii

CBS domains are small protein motifs, usually associated in tandem, that are implicated in binding to adenosyl groups. Several genetic diseases in humans have been associated with mutations in CBS sequences, which has made them very promising targets for rational drug design. Trigonal crystals of th...

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Main Authors: Fernández-Millán, Pablo, Kortazar, Danel, Lucas, María, Martínez-Chantar, María Luz, Astigarraga, Egoitz, Fernández, José Andrés, Sabas, Olatz, Albert, Armando, Mato, Jose M., Martínez-Cruz, Luis Alfonso
Format: Artigo
Sprog:Inglês
Udgivet: International Union of Crystallography 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443959/
https://ncbi.nlm.nih.gov/pubmed/18607087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108013432
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