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Posaconazole Enhances the Activity of Amphotericin B against Hyphae of Zygomycetes In Vitro

The in vitro activity of posaconazole plus amphotericin B against conidia and hyphae of 30 clinical zygomycetes was investigated. The combination of posaconazole with amphotericin B was found to be significantly more synergistic (40%) against hyphae (P < 0.05) than against conidia (10%). Antagoni...

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Detalhes bibliográficos
Main Authors: Perkhofer, Susanne, Locher, Maria, Cuenca-Estrella, Manuel, Rüchel, Reinhard, Würzner, Reinhard, Dierich, Manfred P., Lass-Flörl, Cornelia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443899/
https://ncbi.nlm.nih.gov/pubmed/18458135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00492-08
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