Acquisition of a Plasmid-Borne bla(OXA-58) Gene with an Upstream IS1008 Insertion Conferring a High Level of Carbapenem Resistance to Acinetobacter baumannii

The oxacillinase gene was reported to confer limited resistance to carbapenem in Acinetobacter baumannii. In this study, we have demonstrated that an A. baumannii clinical isolate harboring a plasmid, pTVICU53, has 11,037 bp encoding 13 open reading frames. A bla(OXA-58) gene with an upstream insert...

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Bibliographic Details
Main Authors: Chen, Te-Li, Wu, Roy Chen-Chih, Shaio, Men-Fang, Fung, Chang-Phone, Cho, Wen-Long
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443897/
https://ncbi.nlm.nih.gov/pubmed/18443121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00393-08
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