In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus

Rifamycins have proven efficacy in the treatment of persistent bacterial infections. However, the frequency with which bacteria develop resistance to rifamycin agents restricts their clinical use to antibiotic combination regimens. In a program directed toward the synthesis of rifamycins with a lowe...

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Opis bibliograficzny
Główni autorzy: Robertson, Gregory T., Bonventre, Eric J., Doyle, Timothy B., Du, Qun, Duncan, Leonard, Morris, Timothy W., Roche, Eric D., Yan, Dalai, Lynch, A. Simon
Format: Artigo
Język:Inglês
Wydane: American Society for Microbiology (ASM) 2008
Hasła przedmiotowe:
Mechanisms of Action: Physiological Effects
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443886/
https://ncbi.nlm.nih.gov/pubmed/18443108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01649-07
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