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In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus
Rifamycins have proven efficacy in the treatment of persistent bacterial infections. However, the frequency with which bacteria develop resistance to rifamycin agents restricts their clinical use to antibiotic combination regimens. In a program directed toward the synthesis of rifamycins with a lowe...
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Hauptverfasser: | , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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American Society for Microbiology (ASM)
2008
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443886/ https://ncbi.nlm.nih.gov/pubmed/18443108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01649-07 |
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