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In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus

Rifamycins have proven efficacy in the treatment of persistent bacterial infections. However, the frequency with which bacteria develop resistance to rifamycin agents restricts their clinical use to antibiotic combination regimens. In a program directed toward the synthesis of rifamycins with a lowe...

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Autores principales: Robertson, Gregory T., Bonventre, Eric J., Doyle, Timothy B., Du, Qun, Duncan, Leonard, Morris, Timothy W., Roche, Eric D., Yan, Dalai, Lynch, A. Simon
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443886/
https://ncbi.nlm.nih.gov/pubmed/18443108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01649-07
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