In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus

Rifamycins have proven efficacy in the treatment of persistent bacterial infections. However, the frequency with which bacteria develop resistance to rifamycin agents restricts their clinical use to antibiotic combination regimens. In a program directed toward the synthesis of rifamycins with a lowe...

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Bibliographische Detailangaben
Hauptverfasser: Robertson, Gregory T., Bonventre, Eric J., Doyle, Timothy B., Du, Qun, Duncan, Leonard, Morris, Timothy W., Roche, Eric D., Yan, Dalai, Lynch, A. Simon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443886/
https://ncbi.nlm.nih.gov/pubmed/18443108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01649-07
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