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A 52-kDa Leucyl Aminopeptidase from Treponema denticola Is a Cysteinylglycinase That Mediates the Second Step of Glutathione Metabolism

The metabolism of glutathione by the periodontal pathogen Treponema denticola produces hydrogen sulfide, which may play a role in the host tissue destruction seen in periodontitis. H(2)S production in this organism has been proposed to occur via a three enzyme pathway, γ-glutamyltransferase, cystein...

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Bibliografiska uppgifter
Huvudupphovsmän: Chu, Lianrui, Lai, Yanlai, Xu, Xiaoping, Eddy, Scott, Yang, Shuang, Song, Li, Kolodrubetz, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443665/
https://ncbi.nlm.nih.gov/pubmed/18482986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801034200
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