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Involvement of Protective Autophagy in TRAIL Resistance of Apoptosis-defective Tumor Cells
Targeting TRAIL receptors with either recombinant TRAIL or agonistic DR4- or DR5-specific antibodies has been considered a promising treatment for cancer, particularly due to the preferential apoptotic susceptibility of tumor cells over normal cells to TRAIL. However, the realization that many tumor...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443661/ https://ncbi.nlm.nih.gov/pubmed/18375389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710169200 |
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