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Retinal Pigment Epithelium-Retinal G Protein Receptor-Opsin Mediates Light-dependent Translocation of All-trans-retinyl Esters for Synthesis of Visual Chromophore in Retinal Pigment Epithelial Cells

Visual perception begins with the absorption of a photon by an opsin pigment, inducing isomerization of its 11-cis-retinaldehyde chromophore. After a brief period of activation, the resulting all-trans-retinaldehyde dissociates from the opsin apoprotein rendering it insensitive to light. Restoring l...

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Main Authors: Radu, Roxana A., Hu, Jane, Peng, Jennifer, Bok, Dean, Mata, Nathan L., Travis, Gabriel H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443657/
https://ncbi.nlm.nih.gov/pubmed/18474598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801288200
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