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Mutation in murine coronavirus replication protein nsp4 alters assembly of double membrane vesicles

Coronaviruses are positive-strand RNA viruses that replicate in the cytoplasm of infected cells by generating a membrane-associated replicase complex. The replicase complex assembles on double membrane vesicles (DMVs). Here, we studied the role of a putative replicase anchor, nonstructural protein 4...

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Détails bibliographiques
Auteurs principaux: Clementz, Mark A., Kanjanahaluethai, Amornrat, O'Brien, Timothy E., Baker, Susan C.
Format: Artigo
Langue:Inglês
Publié: Elsevier Inc. 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443636/
https://ncbi.nlm.nih.gov/pubmed/18295294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.01.018
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