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Regulation of the Nitric Oxide Pathway Genes by Tetrahydrofurandiols: Microarray Analysis of MCF-7 Human Breast Cancer Cells

THF-diols (9,12-oxy-10,13-dihydroxyoctadecanoic and 10,13-oxy-9,12-dihydroxyoctadecanoic acids) are endocrine disrupters in rats and mitogens in breast cancer cells. Microarray analyses and real-time PCR analyses on RNA from THF-treated MCF-7 cells revealed a number of genes (Caveolin 1, Heat Shock...

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Autors principals: Shoulars, Kevin, Rodriguez, Mary Ann, Thompson, Trellis, Turk, John, Crowley, Jan, Markaverich, Barry M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443634/
https://ncbi.nlm.nih.gov/pubmed/18346845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2008.01
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