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E1 Ubiquitin-Activating Enzyme UBA-1 Plays Multiple Roles throughout C. elegans Development
Poly-ubiquitination of target proteins typically marks them for destruction via the proteasome and provides an essential mechanism for the dynamic control of protein levels. The E1 ubiquitin-activating enzyme lies at the apex of the ubiquitination cascade, and its activity is necessary for all subse...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2008
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2443343/ https://ncbi.nlm.nih.gov/pubmed/18636104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000131 |
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