Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer

Aromatic amines, N-nitroso compounds and heterocyclic amines are suspected human pancreatic carcinogens. Cytochrome P450 (CYP) 1A2, N-acetyltransferase (NAT) 1, NAT2 and sulfotransferase (SULT) are enzymes involved in the metabolism of these carcinogens. To test the hypothesis that genetic variation...

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Detalhes bibliográficos
Main Authors: Suzuki, Hideo, Morris, Jeffrey S., Li, Yanan, Doll, Mark A., Hein, David W., Liu, Jun, Jiao, Li, Hassan, Manal M., Day, Rena S., Bondy, Melissa L., Abbruzzese, James L., Li, Donghui
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Molecular Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443278/
https://ncbi.nlm.nih.gov/pubmed/18499698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn085
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