Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

BACKGROUND: Vaccination of macaques with live attenuated simian immunodeficiency virus (SIV) provides significant protection against the wild-type virus. The use of a live attenuated human immunodeficiency virus (HIV) as AIDS vaccine in humans is however considered unsafe because of the risk that th...

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Detalhes bibliográficos
Main Authors: Das, Atze T, Klaver, Bep, Centlivre, Mireille, Harwig, Alex, Ooms, Marcel, Page, Mark, Almond, Neil, Yuan, Fang, Piatak, Mike, Lifson, Jeffrey D, Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443169/
https://ncbi.nlm.nih.gov/pubmed/18533993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-44
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