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Human brain myelination and amyloid beta deposition in Alzheimer’s disease
We hypothesized that myelin breakdown in vulnerable late-myelinating regions releases oligodendrocyte- and myelin-associated iron that promotes amyloid beta (Aβ) oligomerization, its associated toxicity, and the deposition of oligomerized Aβ and iron in neuritic plaques observed in Alzheimer’s disea...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442864/ https://ncbi.nlm.nih.gov/pubmed/18596894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2007.01.019 |
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