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Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction
A large range of neuroadaptations develop in response to chronic opioid exposure and these are thought to be more or less critical for expression of the major features of opioid addiction: tolerance, withdrawal and processes that may contribute to compulsive use and relapse. This review considers th...
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| Format: | Artigo |
| Jezik: | Inglês |
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Nature Publishing Group
2008
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442443/ https://ncbi.nlm.nih.gov/pubmed/18414400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.100 |
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