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Functional Requirement for Orai1 in Store-operated TRPC1-STIM1 Channels

Orai1 and TRPC1 have been proposed as core components of store-operated calcium release-activated calcium (CRAC) and store-operated calcium (SOC) channels, respectively. STIM1, a Ca(2+) sensor protein in the endoplasmic reticulum, interacts with and mediates store-dependent regulation of both channe...

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Autors principals: Cheng, Kwong Tai, Liu, Xibao, Ong, Hwei Ling, Ambudkar, Indu S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442339/
https://ncbi.nlm.nih.gov/pubmed/18326500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800008200
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