Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis: A LINK TO CERAMIDE SYNTHASE-3

Previously, it was found that a novel class of neutral fucosylated glycosphingolipids (GSLs) is required for male fertility. These lipids contain very long-chain (C26-C32) polyunsaturated (4-6 double bonds) fatty acid residues (VLC-PUFAs). To assess the role of these complex GSLs in spermatogenesis,...

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Main Authors: Rabionet, Mariona, van der Spoel, Aarnoud C., Chuang, Chia-Chen, von Tümpling-Radosta, Benita, Litjens, Manja, Bouwmeester, Diane, Hellbusch, Christina C., Körner, Christian, Wiegandt, Herbert, Gorgas, Karin, Platt, Frances M., Gröne, Hermann-Josef, Sandhoff, Roger
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442322/
https://ncbi.nlm.nih.gov/pubmed/18308723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800870200
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