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Massive Ca-induced Membrane Fusion and Phospholipid Changes Triggered by Reverse Na/Ca Exchange in BHK Fibroblasts

Baby hamster kidney (BHK) fibroblasts increase their cell capacitance by 25–100% within 5 s upon activating maximal Ca influx via constitutively expressed cardiac Na/Ca exchangers (NCX1). Free Ca, measured with fluo-5N, transiently exceeds 0.2 mM with total Ca influx amounting to ∼5 mmol/liter cell...

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Detalhes bibliográficos
Main Authors: Yaradanakul, Alp, Wang, Tzu-Ming, Lariccia, Vincenzo, Lin, Mei-Jung, Shen, Chengcheng, Liu, Xinran, Hilgemann, Donald W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442179/
https://ncbi.nlm.nih.gov/pubmed/18562498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709865
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