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Evaluation of Screening Strategies for Pre-malignant Lesions using a Biomathematical Approach

We derive mathematical expressions for the size distribution of screen-detectable pre-malignant lesions, both conditional and unconditional on no prior detection of cancer in the tissue of interest, based on a general multistage clonal expansion model of carcinogenesis. We apply these expressions to...

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Detalhes bibliográficos
Main Authors: Jeon, Jihyoun, Meza, Rafael, Moolgavkar, Suresh H., Georg Luebeck, E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442130/
https://ncbi.nlm.nih.gov/pubmed/18374369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2008.02.006
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