Human pregnane X receptor is expressed in breast carcinomas, potential heterodimers formation between hPXR and RXR-alpha

BACKGROUND: The human pregnane X receptor (hPXR) is an orphan nuclear receptor that induces transcription of response elements present in steroid-inducible cytochrome P-450 gene promoters. This activation requires the participation of retinoid X receptors (RXRs), needed partners of hPXR to form hete...

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Main Authors: Conde, Isabel, Lobo, María VT, Zamora, Javier, Pérez, Julio, González, Francisco J, Alba, Emilio, Fraile, Benito, Paniagua, Ricardo, Arenas, María I
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2442113/
https://ncbi.nlm.nih.gov/pubmed/18565212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-174
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