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Structure determination of a Galectin-3–carbohydrate complex using paramagnetism-based NMR constraints
The determination of the location and conformation of a natural ligand bound to a protein receptor is often a first step in the rational design of molecules that can modulate receptor function. NMR observables, including NOEs, often provide the basis for these determinations. However, when ligands a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2442008/ https://ncbi.nlm.nih.gov/pubmed/18413860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.034561.108 |
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