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Extracellular plasma RNA from colon cancer patients is confined in a vesicle-like structure and is mRNA-enriched

Little is yet known about the origin and protective mechanism of free nucleic acids in plasma. We investigated the possibility of these free nucleic acids being particle associated. Plasma samples from colon cancer patients and cell culture media were subjected to various antibody incubations, ultra...

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Detalhes bibliográficos
Main Authors: García, José Miguel, García, Vanesa, Peña, Cristina, Domínguez, Gemma, Silva, Javier, Diaz, Raquel, Espinosa, Pablo, Citores, Maria Jesús, Collado, Manuel, Bonilla, Félix
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441977/
https://ncbi.nlm.nih.gov/pubmed/18456845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.755908
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