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Metabolic Basis of Visual Cycle Inhibition by Retinoid and Nonretinoid Compounds in the Vertebrate Retina

In vertebrate retinal photoreceptors, the absorption of light by rhodopsin leads to photoisomerization of 11-cis-retinal to its all-trans isomer. To sustain vision, a metabolic system evolved that recycles all-trans-retinal back to 11-cis-retinal. The importance of this visual (retinoid) cycle is un...

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Detalhes bibliográficos
Main Authors: Golczak, Marcin, Maeda, Akiko, Bereta, Grzegorz, Maeda, Tadao, Kiser, Philip D., Hunzelmann, Silke, von Lintig, Johannes, Blaner, William S., Palczewski, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441898/
https://ncbi.nlm.nih.gov/pubmed/18195010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708982200
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