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The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes

Rho-kinase inhibitor Y-27632 (Y-27) affects actomyosin cytoskeletal networks and has been shown to significantly increase outflow facility (C) in enucleated porcine and rabbit eyes, as well as in vivo monkey eyes without obvious toxicity. The mechanisms underlying these responses remain largely unkn...

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Detalhes bibliográficos
Main Authors: Lu, Zhaozeng, Overby, Darryl R., Scott, Patrick A., Freddo, Thomas F., Gong, Haiyan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441864/
https://ncbi.nlm.nih.gov/pubmed/18155193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2007.10.018
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