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Structural and evolutionary classification of Type II restriction enzymes based on theoretical and experimental analyses

For a very long time, Type II restriction enzymes (REases) have been a paradigm of ORFans: proteins with no detectable similarity to each other and to any other protein in the database, despite common cellular and biochemical function. Crystallographic analyses published until January 2008 provided...

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Detalhes bibliográficos
Main Authors: Orlowski, Jerzy, Bujnicki, Janusz M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441816/
https://ncbi.nlm.nih.gov/pubmed/18456708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn175
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